Breathing and metal artifact reduction in combined PET/CT imaging

C. van der Vos

Promotor: L. de Geus-Oei
Copromotor: E. Visser
November 16, 2017


The sensitivity of PET and the possibility to quantitatively analyse PET images makes PET an essential tool for cancer imaging. However, PET does have several drawbacks. The two main limitations are the relatively low spatial resolution, in the range of millimetres, which results in a partial-volume effect affecting images both visually and quantitatively, and secondly, the generally low signal-to-noise ratio, which also reduces the quality of the images. In recent years, multiple advances have been achieved in PET/CT hardware, software and acquisition methods, which potentially improve quantification and small lesion detection. In chapter 2 these recent advances in PET/CT technology and the potential consequences of these developments for the EANM guidelines and EARL accreditation for 18F-FDG PET/CT imaging are explained. This chapter also introduces both respiratory gating and metal artefact reduction as potential tool to solve attenuation correction artefacts. These subjects are further discussed in the following chapters of this thesis

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