Radboud Imaging Publications

most cited

Accepted or to appear

  1. M. Ghafoorian, N. Karssemeijer, T. Heskes, I. van Uden, C. Sanchez, G. Litjens, F.-E. de Leeuw, B. van Ginneken, E. Marchiori and B. Platel. "Location Sensitive Deep Convolutional Neural Networks for Segmentation of White Matter Hyperintensities", Nature Scientific Reports.

  2. K. Chung, C. Jacobs, E.T. Scholten, O.M. Mets, I. Dekker, M. Prokop, B. van Ginneken and C.M. Schaefer-Prokop. "Malignancy estimation of Lung-RADS criteria for subsolid nodules on CT: accuracy of low and high risk spectrum when using NLST nodules", European Radiology. Abstract/PDF DOI PMID 28439653

  3. K. Chung, C. Jacobs, E.T. Scholten, J.M. Goo, H. Prosch, N. Sverzellati, F. Ciompi, O.M. Mets, P.K. Gerke, M. Prokop, B. van Ginneken and C.M. Schaefer-Prokop. "Lung-RADS Category 4X: Does It Improve Prediction of Malignancy in Subsolid Nodules?", Radiology:161624. Abstract/PDF DOI PMID 28339311

  4. S.J. van Riel, F. Ciompi, C. Jacobs, M.M. Winkler Wille, E.T. Scholten, M. Naqibullah, S. Lam, M. Prokop, C. Schaefer-Prokop and B. van Ginneken. "Malignancy risk estimation of screen-detected nodules at baseline CT: comparison of the PanCan model, Lung-RADS and NCCN guidelines", European Radiology. Abstract/PDF DOI PMID 28293773

  5. L. Hogeweg, C.I. Sánchez, P. Maduskar, R.H.H.M. Philipsen and B. van Ginneken. "Fast and effective quantification of symmetry in medical images for pathology detection: application to chest radiography", Medical Physics. Abstract DOI PMID 28134985

  6. E. Pompe, P.A. de Jong, D.A. Lynch, N. Lessmann, I. Išgum, B. van Ginneken, J.-W. Lammers and F.A. Mohamed Hoesein. "Computed tomographic findings in subjects who died from respiratory disease in the National Lung Screening Trial", European Respiratory Journal. Abstract DOI

  7. J. Barentsz, M. de Rooij, G. Villeirs and J. Weinreb. "Prostate Imaging-Reporting and Data System Version 2 and the Implementation of High-quality Prostate Magnetic Resonance Imaging.", European urology. DOI PMID 28262414

  8. M.A.H. Berrevoets, I.J.E. Kouijzer, E.H.J.G. Aarntzen, M.J.R. Janssen, L.-F. De Geus-Oei, H.F.L. Wertheim, B.-J. Kullberg, J. Ten Oever, W.J.G. Oyen and C.P. Bleeker-Rovers. "(18)F-FDG-PET/CT optimizes treatment in Staphylococcus aureus bacteremia and is associated with reduced mortality.", Journal of nuclear medicine : official publication, Society of Nuclear Medicine. Abstract DOI PMID 28336786

  9. J.G. Cohen, H. Kim, S.B. Park, B. van Ginneken, G.R. Ferretti, C.H. Lee, J.M. Goo and C.M. Park. "Comparison of the effects of model-based iterative reconstruction and filtered back projection algorithms on software measurements in pulmonary subsolid nodules", European Radiology. Abstract/PDF DOI PMID 28058482

  10. A.S. Fortuin, R. Brüggemann, J. van der Linden, I. Panfilov, B. Israël, T.W.J. Scheenen and J.O. Barentsz. "Ultra-small superparamagnetic iron oxides for metastatic lymph node detection: back on the block.", Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology. Abstract DOI PMID 28382713

  11. I. van der Kroon, W. Woliner-van der Weg, M. Brom, L. Joosten, C. Frielink, M.W. Konijnenberg, E.P. Visser and M. Gotthardt. "Whole organ and islet of Langerhans dosimetry for calculation of absorbed doses resulting from imaging with radiolabeled exendin.", Scientific reports;7:39800. Abstract DOI PMID 28067253

  12. P.J. van Leeuwen, A. Hayen, J.E. Thompson, D. Moses, R. Shnier, M. B�hm, M. Abuodha, A.-M. Haynes, F. Ting, J. Barentsz, M. Roobol, J. Vass, K. Rasiah, W. Delprado and P.D. Stricker. "A Multiparametric Magnetic Resonance Imaging Based Risk Model to Determine the Risk of Significant Prostate Cancer prior to biopsy.", BJU international. Abstract DOI PMID 28207981

  13. F.J.A. Meijer, B. Goraj, B.R. Bloem and R.A.J. Esselink. "How I do it: Clinical Application of Brain MRI in the Diagnostic Work-up of Parkinsonism.", Journal of Parkinson's disease. Abstract DOI PMID 28282809

  14. T. Mertzanidou, J.H. Hipwell, S. Reis, D.J. Hawkes, B. Ehteshami Bejnordi, M. Dalmis, S. Vreemann, B. Platel, J. van der Laak, N. Karssemeijer, M. Hermsen, P. Bult and R. Mann. "3D volume reconstruction from serial breast specimen radiographs for mapping between histology and 3D whole specimen imaging", Medical Physics. DOI

  15. J.-J. Mordang, A. Gubern-Merida, A. Bria, F. Tortorella, G. den Heeten and N. Karssemeijer. "Improving computer-aided detection assistance in breast cancer screening by removal of obviously false-positive findings", Medical Physics. Abstract/PDF DOI PMID 28182277

  16. R.A. Nadar, N. Margiotta, M. Iafisco, J.J.J.P. van den Beucken, O.C. Boerman and S.C.G. Leeuwenburgh. "Bisphosphonate-Functionalized Imaging Agents, Anti-Tumor Agents and Nanocarriers for Treatment of Bone Cancer.", Advanced healthcare materials. Abstract DOI PMID 28207199

  17. S.M.B. Peters, D. Zweers, F. de Lange and J.E.M. Mourik. "LEAD COMPOSITE VS. NONLEAD PROTECTIVE GARMENTS: WHICH ARE BETTER? A MULTIVENDOR COMPARISON.", Radiation protection dosimetry. Abstract DOI PMID 28074020

  18. A. Rodriguez-Ruiz, S.S.J. Feng, J. van Zelst, S. Vreemann, J. Rice Mann, C.J. D'Orsi and I. Sechopoulos. "Improvements of an objective model of compressed breasts undergoing mammography: Generation and characterization of breast shapes.", Medical physics. Abstract DOI PMID 28244109

  19. M.G. Schouten, M. van der Leest, M. Pokorny, M. Hoogenboom, J.O. Barentsz, L.C. Thompson and J.J. F�tterer. "Why and Where do We Miss Significant Prostate Cancer with Multi-parametric Magnetic Resonance Imaging followed by Magnetic Resonance-guided and Transrectal Ultrasound-guided Biopsy in Biopsy-na�ve Men?", European urology. Abstract DOI PMID 28063613

  20. S.C.A. Steens, E.M. Bekers, W.L.J. Weijs, G.J.S. Litjens, A. Veltien, A. Maat, G.B. van den Broek, J.A.W.M. van der Laak, J.J. Fütterer, C.A.H. van der Kaa, M.A.W. Merkx and R.P. Takes. "Evaluation of tongue squamous cell carcinoma resection margins using ex-vivo MR.", International journal of computer assisted radiology and surgery. Abstract DOI PMID 28130702

  21. N. Tayari, A. Heerschap, T.W.J. Scheenen and T. Kobus. "In vivo MR spectroscopic imaging of the prostate, from application to interpretation.", Analytical biochemistry. Abstract DOI PMID 28167072

  22. W. Venderink, A. van Luijtelaar, J.G.R. Bomers, M. van der Leest, C. Hulsbergen-van de Kaa, J.O. Barentsz, J.P.M. Sedelaar and J.J. F�tterer. "Results of Targeted Biopsy in Men with Magnetic Resonance Imaging Lesions Classified Equivocal, Likely or Highly Likely to Be Clinically Significant Prostate Cancer.", European urology. Abstract/PDF DOI PMID 28258784


  1. M.U. Dalmis, G. Litjens, K. Holland, A. Setio, R. Mann, N. Karssemeijer and A. Gubern-Mérida. "Using deep learning to segment breast and fibroglandular tissue in MRI volumes", Medical Physics 2017;44:533-546. Abstract/PDF DOI PMID 28035663

  2. K. Holland, A. Gubern-Mérida, R.M. Mann and N. Karssemeijer. "Optimization of volumetric breast density estimation in digital mammograms", Physics in Medicine and Biology 2017;62(9):3779-3797. Abstract/PDF DOI

  3. B. van Ginneken. "Fifty years of computer analysis in chest imaging: rule-based, machine learning, deep learning", Radiological Physics and Technology 2017;10(1):23-32. Abstract/PDF DOI PMID 28211015

  4. R. Manniesing, M.T. Oei, L.J. Oostveen, J. Melendez, E.J. Smit, B. Platel, C.I. Sánchez, F.J. Meijer, M. Prokop and B. van Ginneken. "White Matter and Gray Matter Segmentation in 4D Computed Tomography", Nature Scientific Reports 2017;7(119). Abstract/PDF DOI PMID 28273920

  5. K. Holland, C.H. van Gils, R.M. Mann and N. Karssemeijer. "Quantification of masking risk in screening mammography with volumetric breast density maps", Breast Cancer Research and Treatment 2017;162(3):541-548. Abstract/PDF DOI

  6. R. Hernandez, S. Heskamp, M. Rijpkema, D. #. e. #. e.L. Bos, D.M. Goldenberg, W.J. McBride, A. Morgenstern, F. Bruchertseifer, W. Cai and O.C. Boerman. "Preventing Radiobleaching of Cyanine Fluorophores Enhances Stability of Nuclear/NIRF Multimodality Imaging Agents", Theranostics 2017;7(1):1-8. PDF

  7. J.O.P. Wanders, K. Holland, W.B. Veldhuis, R.M. Mann, R.M. Pijnappel, P.H.M. Peeters, C.H. van Gils and N. Karssemeijer. "Volumetric breast density affects performance of digital screening mammography.", Breast Cancer Research and Treatment 2017;162(1):95-103. Abstract/PDF DOI PMID 28012087

  8. M.W. Kroes, W.M.H. Busser, Y.L. Hoogeveen, F. de Lange and L.J. Schultze Kool. "Laser Guidance in C-Arm Cone-Beam CT-Guided�Radiofrequency Ablation of Osteoid Osteoma Reduces Fluoroscopy Time.", Cardiovascular and interventional radiology 2017;40(5):728-734. Abstract/PDF DOI PMID 27942926

  9. T.F.M. Wijnands, A.P.M. Görtjes, T.J.G. Gevers, S.F.M. Jenniskens, L.J.S. Kool, A. Potthoff, M. Ronot and J.P.H. Drenth. "Efficacy and Safety of Aspiration Sclerotherapy of Simple Hepatic Cysts: A Systematic Review.", AJR. American journal of roentgenology 2017;208:201-207. Abstract/PDF DOI PMID 27824501

  10. L.T. van der Meer, S.Y.A. Terry, D. van Ingen Schenau, K.C. Andree, G.M. Franssen, D.M. Roeleveld, B.M. Metselaar, T. Reinheckel, P.M. Hoogerbrugge, O.C. Boerman and F.N. van Leeuwen. "In vivo imaging of antileukemic drug asparaginase reveals a rapid macrophage mediated clearance from the bone marrow.", Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2017;58(2):214-220. Abstract/PDF DOI PMID 27493268

  11. A. Patel, B. van Ginneken, F.J.A. Meijer, E.J. van Dijk, M. Prokop and R. Manniesing. "Robust Cranial Cavity Segmentation in CT and CT Perfusion Images of Trauma and Suspected Stroke Patients", Medical Image Analysis 2017;36:216-228. Abstract/PDF DOI PMID 28011374

  12. J. Charbonnier, E. van Rikxoort, A. Setio, C. Schaefer-Prokop, B. van Ginneken and F. Ciompi. "Improving Airway Segmentation in Computed Tomography using Leak Detection with Convolutional Networks", Medical Image Analysis 2017;36:52-60. Abstract/PDF DOI

  13. C. Smids, I.J.E. Kouijzer, F.J. Vos, T. Sprong, A.J.F. Hosman, J.W.J. de Rooy, E.H.J.G. Aarntzen, L.-F. de Geus-Oei, W.J.G. Oyen and C.P. Bleeker-Rovers. "A comparison of the diagnostic value of MRI and (18)F-FDG-PET/CT in suspected spondylodiscitis.", Infection 2017;45(1):41-49. Abstract/PDF DOI PMID 27317050

  14. U. Yousaf-Khan, C. van der Aalst, P.A. de Jong, M. Heuvelmans, E. Scholten, J.-W. Lammers, P. van Ooijen, K. Nackaerts, C. Weenink, H. Groen, R. Vliegenthart, K. Ten Haaf, M. Oudkerk and H. de Koning. "Final screening round of the NELSON lung cancer screening trial: the effect of a 2.5-year screening interval.", Thorax 2017;72)(1):48-56. Abstract/PDF DOI PMID 27364640

  15. O.M. Mets, P.A. de Jong, E.T. Scholten, K. Chung, B. van Ginneken and C.M. Schaefer-Prokop. "Subsolid pulmonary nodule morphology and associated patient characteristics in a routine clinical population", European Radiology 2017;27(2):689-696. Abstract/PDF DOI PMID 27255399

  16. I.K. Steinseifer, B.W.J. Philips, B. Gagoski, E. Weiland, T.W.J. Scheenen and A. Heerschap. "Flexible proton 3D MR spectroscopic imaging of the prostate with low-power adiabatic pulses for volume selection and spiral readout.", Magn Reson Med 2017;77(3):928-935. Abstract/PDF DOI PMID 26968422

  17. I.A.C. Arnoldussen, M. Wiesmann, C.E. Pelgrim, E.M. Wielemaker, W. van Duyvenvoorde, P.L. Amaral-Santos, L. Verschuren, B.J.F. Keijser, A. Heerschap, R. Kleemann, P.Y. Wielinga and A.J. Kiliaan. "Butyrate restores HFD-induced adaptations in brain function and metabolism in mid-adult obese mice.", International journal of obesity (2005) 2017:1-10. Abstract DOI PMID 28220041

  18. R.J. van den Bijgaart, D.C. Eikelenboom, M. Hoogenboom, J.J. Fütterer, M.H. den Brok and G.J. Adema. "Thermal and mechanical high-intensity focused ultrasound: perspectives on tumor ablation, immune effects and combination strategies", Cancer Immunology, Immunotherapy 2017;66:247-58.

  19. F. Ciompi, K. Chung, S.J. van Riel, A.A.A. Setio, P.K. Gerke, C. Jacobs, E.T. Scholten, C.M. Schaefer-Prokop, M.M.W. Wille, A. Marchiano, U. Pastorino, M. Prokop and B. van Ginneken. "Towards automatic pulmonary nodule management in lung cancer screening with deep learning", Nature Scientific Reports 2017(46479). Abstract DOI

  20. S.U. Dalm, J.F. Verzijlbergen and M. De Jong. "Review: Receptor Targeted Nuclear Imaging of Breast Cancer.", International journal of molecular sciences 2017;18. Abstract/PDF DOI PMID 28134770

  21. K. Daoudi, M. Hoogenboom, M. den Brok, D. Eikelenboom, G.J. Adema, Jü.J. Fütterer and C.L. de Korte. "In vivo photoacoustics and high frequency ultrasound imaging of mechanical high intensity focused ultrasound (HIFU) ablation", Biomedical Optics Express 2017;8(4):2235-2244.

  22. A.A.J. van Esch, J.P.H. Drenth and J.J. Hermans. "Specific Radiological Imaging Findings in Patients With Hereditary Pancreatitis During a Long Follow-up of Disease.", Pancreas 2017;46(3):372-379. Abstract/PDF DOI PMID 28129231

  23. K. Gijsbertse, A.M.J. Sprengers, M.M. Nillesen, H.H.G. Hansen, R.G.P. Lopata, N. Verdonschot and C.L. de Korte. "Three-dimensional ultrasound strain imaging of skeletal muscles.", Physics in medicine and biology 2017;62:596-611. Abstract/PDF DOI PMID 28033112

  24. M. Hoogenboom, D.C. Eikelenboom, R.J. van den Bijgaart, A. Heerschap, P. Wesseling, M.H. den Brok, J.J. Fütterer and G.J. Adema. "Impact of MR-guided boiling histotripsy in distinct murine tumor models", Ultrasonics Sonochemistry 2017;38:1-8.

  25. S.E.R. Horbach, D.T. Ubbink, F.E. Stubenrouch, M.J.W. Koelemay, C.J.M. van der Vleuten, B.H. Verhoeven, J.A. Reekers, L.J. Schultze Kool and C.M.A.M. van der Horst. "Shared Decision-Making in the Management of Congenital Vascular Malformations.", Plastic and reconstructive surgery 2017;139:725e-734e. Abstract DOI PMID 28234848

  26. J. Kadziela, A. Prejbisz, I. Michalowska, S. Kolodziejczyk-Kruk, L. Schultze Kool, M. Kabat, H. Janaszek-Sitkowska, S. Toutounchi, Z. Galazka, U. Ambroziak, T. Bednarczuk, D. Ptasi?ska-Wnuk, M. Hoffmann, M. Januszewicz, A. Januszewicz and A. Witkowski. "A single-centre experience of the implementation of adrenal vein sampling procedure: the impact on the diagnostic work-up in primary aldosteronism.", Kardiologia polska 2017;75:28-34. Abstract DOI PMID 27878800

  27. W.M. Klein, M.E. Van der Putten, B. Kusters and B.H. Verhoeven. "Fatal Complications after Pediatric Surgical Interventions: Lessons Learned.", European journal of pediatric surgery reports 2017;5:e12-e16. Abstract DOI PMID 28344917

  28. T. Kooi and N. Karssemeijer. "Classifying Symmetrical Differences and Temporal Change in Mammography Using Deep Neural Networks" 2017. Abstract

  29. M.W. Kroes, W.M.H. Busser, Y.L. Hoogeveen, F. de Lange and L.J. Schultze Kool. "Laser Guidance in C-Arm Cone-Beam CT-Guided�Radiofrequency Ablation of Osteoid Osteoma Reduces Fluoroscopy Time.", Cardiovascular and interventional radiology 2017;40:728-734. Abstract DOI PMID 27942926

  30. H. MacMahon, D.P. Naidich, J.M. Goo, K.S. Lee, A.N.C. Leung, J.R. Mayo, A.C. Mehta, Y. Ohno, C.A. Powell, M. Prokop, G.D. Rubin, C.M. Schaefer-Prokop, W.D. Travis, P.E. Van Schil and A.A. Bankier. "Guidelines for Management of Incidental Pulmonary Nodules Detected on CT Images: From the Fleischner Society 2017.", Radiology 2017:161659. Abstract/PDF DOI PMID 28240562

  31. M.F.H. Maessen, T.M.H. Eijsvogels, A. Grotens, M.T.E. Hopman, D.H.J. Thijssen and H.H.G. Hansen. "Feasibility and relevance of compound strain imaging in non-stenotic arteries: comparison between individuals with cardiovascular diseases and healthy controls.", Cardiovascular ultrasound 2017;15:13. Abstract DOI PMID 28521772

  32. S.A.H. Pegge, S.C.A. Steens, H.P.M. Kunst and F.J.A. Meijer. "Pulsatile Tinnitus: Differential Diagnosis and Radiological Work-Up.", Current radiology reports 2017;5:5. Abstract DOI PMID 28203490

  33. S.M.B. Peters, D. Zweers, F. de Lange and J.E.M. Mourik. "LEAD COMPOSITE VS. NONLEAD PROTECTIVE GARMENTS: WHICH ARE BETTER? A MULTIVENDOR COMPARISON.", Radiation protection dosimetry 2017. Abstract DOI PMID 28074020

  34. J.T. Powell, M.J. Sweeting, P. Ulug, J.D. Blankensteijn, F.A. Lederle, J.-P. Becquemin, R.M. Greenhalgh, O. EVAR-1, DREAM and A. Trialists. "Meta-analysis of individual-patient data from EVAR-1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years.", The British journal of surgery 2017;104:166-178. Abstract DOI PMID 28160528

  35. M.H. Tesselaar, T. Crezee, H.G. Swarts, D. Gerrits, O.C. Boerman, J.B. Koenderink, H.G. Stunnenberg, M.G. Netea, J.W. Smit, R.T. Netea-Maier and T.S. Plantinga. "Digitalis-like compounds facilitate non-medullary thyroid cancer redifferentiation through intracellular Ca2+, FOS and autophagy dependent pathways.", Molecular cancer therapeutics 2017;16(1):169-181. Abstract DOI PMID 27837029

  36. M. Wiesmann, V. Zerbi, D. Jansen, D. Lütjohann, A. Veltien, A. Heerschap and A.J. Kiliaan. "Hypertension, cerebrovascular impairment, and cognitive decline in aged A$PP/PS1 mice", Theranostics 2017(7):1277-1289. DOI

  37. M. Wiesmann, B. Zinnhardt, D. Reinhardt, S. Eligehausen, L. Wachsmuth, S. Hermann, P.J. Dederen, M. Hellwich, M.T. Kuhlmann, L.M. Broersen, A. Heerschap, A.H. Jacobs and A.J. Kiliaan. "A specific dietary intervention to restore brain structure and function after ischemic stroke.", Theranostics 2017;7:493-512. Abstract/PDF DOI PMID 28255345