Welcome to the research website of the Department of Radiology and Nuclear Medicine at Radboud university medical center, Nijmegen.
Our research has a strong focus on early detection and early treatment of common diseases. It covers fundamental research on a molecular level, development of new medical devices and software tools, and translates these results to clinical applications that can be used in daily routine. Our mission is to bridge the gap between research and practice and to help shape the future of healthcare. We use technology to make healthcare more affordable by increasing automation of diagnostic and therapeutic procedures, thus freeing manpower for those areas in patient care in which the "human touch" is most needed.
The five fundamental science groups cover ultrasound (MUSIC), biomedical MR (BioMR), diagnostic image analysis (DIAG), nuclear medicine (NucMed) and advanced x-ray tomographic imaging (AXTI). Clinical research is mainly focused on prostate, breast, chest and vascular disease.
Our team published on the successful reintroduction of Combidex-enhanced MRI (nano-MRI) in clinical practice in the Radboudumc. Last week the paper ‘Ultra-small superparamagnetic iron oxides for metastatic lymph node detection: back on the block’ appeared online in the journal Wiley Reviews Nanomedicine and Nanobiotechnology.
Combidex-enhanced MRI at 3 Tesla of a 53-year-old patient with recurrent prostate cancer after radical prostatectomy and radiotherapy (PSA-level 3.9 ng/ml). Twenty-seven hours after administration of Combidex benign lymph nodes have accumulated the contrast agent, becoming black on a 3D iron-sensitive MRI scan. Metastatic lymph nodes retain signal and therefore stay white. A large (7 mm) metastatic lymph node is visible on Combidex MRI as a white spherical structure in two orthogonal planes through the node (blue circles in coronal (A) and axial images (B)). A smaller metastatic white node (2-3 mm) is indicated with red circles in the coronal (C) and axial (D) reconstructions (orthogonal planes through the node of interest) of the 3D data set. The other small spherical structures are blood vessels, best appreciated when scrolling through the 3D image data set.
See more in the Highlight Archive.
For older news, see the News Archive.