Radboud Imaging Research

Welcome to the research website of the Department of Radiology and Nuclear Medicine at Radboud university medical center, Nijmegen.

Our research has a strong focus on early detection and early treatment of common diseases. It covers fundamental research on a molecular level, development of new medical devices and software tools, and translates these results to clinical applications that can be used in daily routine. Our mission is to bridge the gap between research and practice and to help shape the future of healthcare. We use technology to make healthcare more affordable by increasing automation of diagnostic and therapeutic procedures, thus freeing manpower for those areas in patient care in which the "human touch" is most needed.

The five fundamental science groups cover ultrasound (MUSIC), biomedical MR (BioMR), diagnostic image analysis (DIAG), nuclear medicine (NucMed) and advanced x-ray tomographic imaging (AXTI). Clinical research is mainly focused on prostate, breast, chest and vascular disease.

With the menu on the right you can learn more about our researchers, view or download publications or navigate to any of the research groups within the department.

Highlight

Grob et al. have published a paper in European Radiology entitled: Imaging of pulmonary perfusion using subtraction CT angiography is feasible in clinical practice


Subtraction computed tomography (SCT) is a technique that uses software-based motion correction between an unenhanced and an enhanced CT scan for obtaining the iodine distribution in the pulmonary parenchyma. This technique has been implemented in clinical practice for the evaluation of lung perfusion in CT pulmonary angiography (CTPA) in patients with suspicion of acute and chronic pulmonary embolism, with acceptable radiation dose. This paper discusses the technical principles, clinical interpretation, benefits and limitations of arterial subtraction CTPA.


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Key Points: • SCT uses motion correction and image subtraction between an unenhanced and an enhanced CT scan to obtain iodine distribution in the pulmonary parenchyma. • SCT could have an added value in detection of pulmonary embolism. • SCT requires only software implementation, making it potentially more widely available for patient care than dual-energy CT.


See more in the Highlight Archive.

News

  • March 28, 2019: Leticia Gallardo Estrella will defend her PhD thesis titled ''Quantification of COPD biomarkers in thoracic CT scans" at 12.30 in the Aula of the Radboud University.
  • March 26, 2019: Alejandro Rodriguez-Ruiz will defend his PhD thesis titled "Artificial intelligence & tomosynthesis for breast cancer detection" at 12.30 ïn the Aula of the Radboud University.
  • March 18, 2019: Domenico Pangallo joined the AXTI group for his MSc thesis about quantitative image analysis of breast cancer in dedicated breast CT imaging, under the supervision of Marco Caballo.
  • March 10, 2019: Twan Cuijpers joined the AXTI group for his MSc internship. He will work with Joana Boita in a project from LRCB (Dutch Expert Centre for Screening) that intends to create a visualization tool for teaching in mammography.
  • February 26, 2019: Rick Philipsen has succesfully defended his PhD thesis, titled 'Automated chest radiography reading: improvements, validation, and cost-effectiveness analysis'.
  • January 30, 2019: Thomas van den Heuvel defended his thesis on Automated low-cost ultrasound. He showed that a deep learning system can perform real-time detection of risk factors for pregnant women using the input from a low-cost ultrasound device. His work was covered by NOS op 3, national radio, Algemeen Dagblad, Medisch Contact, and RTL Z. Next month, Thomas will return to Ethiopia for further testing of his device.
  • January 24, 2019: Ioannis Sechopoulos was named Fellow of the American Association of Physicists in Medicine ( AAPM) due to his distinguished contributions to medical physics and the esteem in which he is held by his peers
  • January 18, 2019: Roel Verhoeven won the 'Best clinical poster award' at the Imaging the Biomechanics of Life (TOPIM) conference in Les Houches, France as hosted by the European Society for Molecular Imaging. Apart from a great sweater as a rememberance to this award, he more importantly got the opportunity to again present his work as an oral presentation for the main audience!
  • December 20, 2018: Kaj Gijsbertse has succesfully defended his PhD thesis entitled: Functional ultrasound imaging of the lower extremity
  • December 11, 2018: Wulphert Venderink has obtained his PhD.
  • December 11, 2018: Jan Jurre Mordang has succesfully defended his PhD thesis with the title ' Towards an independent observer of screening mammograms: detection of calcifications'.
  • December 7, 2018: Marlene Hekman has obtained her PhD.
  • December 5, 2018: The work by Marco Caballo and Ioannis Sechopoulos about using machine learning to generate super-resolution digital breast phantoms for accurate simulations of new imaging systems, published in Physics in Medicine and Biology, was covered in Physics World and in Aunt Minnie
  • November 27, 2018: Francesco Ciompi and Jeroen van der Laak have been awarded an ICT12 Horizon 2020 grant as part of a consortium of European partners. The goal of this 4-year project, EXA MODE, is to build tools based on artificial intelligence to aid pathologists in routine diagnostics via automatic analysis of digital pathology whole-slide images of cancer specimens across multiple organs.
  • November 23, 2018: Dagmar Grob was awarded for the best 4-slide short talk at the PhD retreat of Radboud Institute for Health Sciences (22 - 23 November 2018)
  • November 5, 2018: Marta Pinto started working as a PhD student at the AXTI group, focusing on image processing algorithms for image quality improvement in digital breast tomosynthesis.
  • October 4, 2018: Peter Laverman, Frank Nijssen and Sandra Heskamp are participating in the project “Advancing Nuclear Medicine – Petten Fieldlab”. In this project we will set up a new fieldlab for the development and market introduction of innovative types of radionuclide therapy. This project is a collaboration between NRG, Radboudumc, NKI-AVL, ErasmusMC, VUMC, FutureChemistry, and NucMed BV. Our group will evaluate the therapeutic efficacy of novel PSMA-targeting ligands radiolabeled with the alpha-emitting radionuclide lead-212 for prostate cancer treatment.

For older news, see the News Archive.